Radix Premnae Microphyllae
Aliases：Xiaoqing Gen; Tu Huangqi (Earth Astragalus; Chinese Materia Medica); Xiaoqingshu Gen; Chouhuangjing Gen; Liangfenchai Gen; Doufumu Gen.
Fubi Root (Root of Japanese Premna) is the name of a traditional Chinese medicine. It is the root of Premna microphylla Turcz., a plant in the family Verbenaceae. It grows under forests on hillsides or at forest edges. It is recorded in Hunan Materia Medica, Fujian Chinese Herbal Medicine, Chinese Materia Medica, and other herbal works.
Efficacy & Actions
Clears Heat and removes toxin.
Indications
Malaria; pediatric summer fever; Wind-Dampness arthralgia; wind-fire toothache; traumatic injuries; scald and burn injuries.
Modern Pharmacology
Modern pharmacological research on Root of Japanese Premna remains insufficient. The following findings are mainly derived from preliminary studies on the root extract of Premna microphylla and related species of the same genus, and are provided for reference: Immune-enhancing effect: The root extract of Premna microphylla enhances the body's non-specific immune function, with one experimental group showing the most significant effect. This study provides a scientific experimental basis for the rational development and utilization of Premna microphylla as a wild medicinal resource. Anti-inflammatory effect: The flavonoid constituents in Root of Japanese Premna possess anti-inflammatory effects. They can inhibit the production and release of inflammatory factors, thereby reducing inflammatory responses. Analgesic effect: The alkaloid constituents in Root of Japanese Premna can block nerve conduction and relieve pain, making it suitable for pain symptoms caused by various reasons. Antibacterial effect: The volatile oils and flavonoid constituents in Root of Japanese Premna possess broad-spectrum antibacterial effects. They can inhibit the growth and reproduction of various bacteria and help prevent and treat infectious diseases. Note: The above pharmacological findings are largely derived from preliminary studies on the root extract of Premna microphylla and related species of the same genus. Dedicated systematic pharmacological research on Root of Japanese Premna is still ongoing. Traditional actions and indications should remain the primary basis for use.
Ingredients
Root of Japanese Premna mainly contains the following active constituents: Flavonoids (principal active constituents): Luteolin Luteolin-7-O-β-D-glucopyranoside Pedalitin Chromones: Eugenin Sterols: β-Sitosterol Organic acids: Palmitic acid trans-p-Methoxycinnamic acid Note: Seven compounds were isolated and identified from the root of Japanese Premna, and all compounds were isolated from this plant for the first time. The above chemical constituent study was published in Subtropical Plant Science, 2002, Issue 3.
Usage & Dosage
Oral use: Decocted in water, 10–15 g; fresh material 30–60 g. External use: Appropriate amount. Pounded and applied topically; or ground into powder and mixed into a paste for topical application.
Contraindications
Pregnant and breastfeeding women should use it under the guidance of a physician. Do not overdose. Use with caution in individuals with Spleen-Stomach deficiency cold.
Selected Formulas
For traumatic injuries (Jiangxi Herbal Medicine Manual) Take 60g of fresh Fubi root bark. Decoct in water, add wine, and take orally. For wind-fire toothache (Fujian Chinese Herbal Medicine) Take 60g of fresh Fubi root. Decoct in water and drink. For venomous snake bites (Fujian Chinese Herbal Medicine) Take fresh Fubi root bark, crush into a paste, and apply to the Tianting acupoint (vertex) and the wound. For burns and scalds (National Exhibition of New TCM Therapies Technical Materials Selection) Take the root bark or leaves of Xiao Qing Shu, dry in the sun, grind into an extremely fine powder, mix with cottonseed oil or vegetable oil, and apply 1–2 times daily.
Medicinal Parts
Root.
Selection & Storage
Dried material should be stored in a well-ventilated, dry place. Protect from moisture and insect damage. Airtight storage is recommended. Avoid direct sunlight. Fresh material should be used promptly or refrigerated for short-term storage.
