Mì Mài É Zhǎng Chái (Dense‑veined Schefflera) is a traditional Chinese medicinal material. It is the dried stem and leaf of Schefflera venulosa (Wight et Arn.) Harms, a plant belonging to the family Araliaceae. It grows in evergreen broad‑leaved forests at altitudes of 900–1,500 meters. It was first recorded in Zhonghua Bencao (Chinese Materia Medica).

Efficacy & Actions

Dispels wind and relieves pain, activates blood circulation and reduces swelling.

Indications

Rheumatic arthralgia; epigastric pain; traumatic injuries and swelling; fractures; traumatic bleeding. It is also used for headache, toothache, dysmenorrhea, and postpartum abdominal pain.

Modern Pharmacology

Anti‑inflammatory and analgesic effects: Its traditional effects of dispelling wind and relieving pain, and activating blood circulation to reduce swelling, are consistent with modern anti‑inflammatory and analgesic activities. Antitumor effects: Studies have found that its extracts exhibit inhibitory activity on the proliferation of certain cancer cells, such as mouse breast cancer tsFT210 cells and human leukemia K562 cells. Treatment of cardiovascular and cerebrovascular diseases: Related research has identified it as a candidate for developing new drugs to treat cardiovascular and cerebrovascular diseases.

Ingredients

Triterpenoids: β‑Amyrin, oleanonic acid, oleanolic acid, and betulinic acid. Sterols: β‑Sitosterol and β‑sitosterol‑β‑D‑glucoside. Organic acids: Chlorogenic acid, neochlorogenic acid, cryptochlorogenic acid, dicaffeoylquinic acid, etc. Others: Saponins, flavonoids, phenols, alkaloids, carbohydrates, etc.

Usage & Dosage

内服:煎汤,9-15g;或浸酒服用。 外用:适量,捣烂敷患处。

Contraindications

Use with caution during pregnancy. Use with caution in patients with qi‑blood deficiency‑weakness. This product is slightly toxic and should be used under the guidance of a physician.

Selected Formulas

For chronic rheumatoid arthritis and traumatic injuries (empirical formula) Take 15-30g of Qiyelian (a local herb), decoct in water and drink. Alternatively, take 120g of the herb, soak in 500g of wine for 48 hours, then take 10ml orally three times daily. Fresh herb may also be crushed and applied externally. For various types of pain (empirical formula) Take 9g of Qiyelian, decoct in water and drink. For pain due to gastric and duodenal ulcers (empirical formula) Take the stem of Qiyelian, decoct in water and drink, or grind into powder and take. For traumatic bleeding (empirical formula) Take the leaves of Qiyelian, crush and apply externally.

Medicinal Parts

It is the dried stem and leaf of Schefflera venulosa (Wight et Arn.) Harms, a plant belonging to the family Araliaceae.

Selection & Storage

Store in a cool, dry place, protected from moisture and insects.