Kāi Kǒu Jiàn (Tupistra chinensis Rhizome) is a traditional Chinese medicinal material. It is the rhizome of Tupistra chinensis Baker and Tupistra ensifolia Wang et Tang, plants belonging to the family Liliaceae.

Efficacy & Actions

Clears heat, removes toxicity, dispels wind-dampness, disperses stasis, and relieves pain.

Indications

Diphtheria, sore throat and tonsillitis, rheumatic arthralgia, rheumatoid arthritis and lumbago with leg pain, traumatic injuries, stomach pain and gastric ulcers, carbuncles, sores and toxic swellings, and snake and rabid dog bites.

Modern Pharmacology

Anti‑inflammatory effects. Antitumor effects. Antioxidant effects. Antibacterial effects. Cardiovascular activity. Expectorant effects.

Ingredients

Steroidal compounds (such as saponins, which are its main active components). Polysaccharides. Volatile oils. Fatty acids. Chlorogenic acid. Flavonoids. Alkaloids. Metal elements.

Usage & Dosage

For oral administration: Decoct in water, 1.5–3 g. Grind into powder, 0.6–0.9 g. For topical application: appropriate amount, mashed for application.

Contraindications

Contraindicated during pregnancy. This product is toxic and should be used under the guidance of a physician. Dosage should not be excessive: There have been reports of poisoning with 9 g. Avoid tobacco, chili peppers, vinegar, and acidic foods (according to Shaanxi Zhongcaoyao — Shaanxi Chinese Herbal Medicine). Symptoms of poisoning: Headache, dizziness, nausea, vomiting, etc. Discontinue immediately and seek emergency treatment. Mechanism of toxicity: Contains rhodexin with digitalis‑like effects; large doses may cause cardiac conduction block and cardiac arrest.

Medicinal Parts

It is the rhizome of Tupistra chinensis Baker and Tupistra ensifolia Wang et Tang, plants belonging to the family Liliaceae.

Selection & Storage

Store in a cool, dry place, protected from moisture and insects.